Article
Disease susceptibility genes and the sib-pair method: a review of recent methodology.
Annals of human genetics - 1 Oct 1994
Shah S, Green J R
Abstract excerpt
There is now a considerable body of literature which describes and analyses various methods of testing for the presence of disease susceptibility genes by examining the degree of HLA haplotype sharing of parental haplotypes over random expectations amongst affected siblings. We here survey a numb...
Topics
- Family
- Female
- Genetic Predisposition to Disease
- HLA Antigens
- Haplotypes
- Humans
- Male
- Matched-Pair Analysis
- Models, Genetic
