Relative risk for genetic associations: the case-parent triad as a variant of case-cohort design.

doi:10.1093/ije/31.3.669

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Article

Relative risk for genetic associations: the case-parent triad as a variant of case-cohort design.

International journal of epidemiology - 1 Jun 2002

Ahsan Habibul, Hodge Susan E, Heiman Gary A, Begg Melissa D, Susser Ezra S

Abstract excerpt

The contribution of this paper is to conceptualize the case-parent triad within an epidemiological framework. We propose that the case-parent triad design is a variant of the case-cohort design. The affected offspring of case-parent triads come from a source cohort of all offspring of parents in a population. We first demonstrate that if the source cohort is restricted to offspring of a certain parental mating...

Topics

Case-Control Studies
Cohort Studies
Genetic Predisposition to Disease
Humans
Models, Statistical
Molecular Epidemiology
Panic Disorder
Research Design
Risk

Source

Open in PubMed

Identifiers

PMID: 12055172
DOI: 10.1093/ije/31.3.669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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