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Article

Using risk-based sampling to enrich cohorts for endpoints, genes, and exposures.

American journal of epidemiology - 15 Aug 2007

Weinberg Clarice R, Shore David L, Umbach David M, Sandler Dale P

Abstract excerpt

Targeting the first-degree relatives of people with a particular complex disease can offer a powerful approach to building a risk-based cohort for prospective studies of etiologic factors. Such a cohort provides both a sizable increase in the rate of accrual of newly incident cases, enriching for risk factors that are known or even unknown, and a high level of motivation among participants. A nationwide study of...

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Identifiers

PMID: 17556763
DOI: 10.1093/aje/kwm097
PMCID: PMC2077981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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