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Article

Parent-child pair design for detecting gene-environment interactions in complex diseases.

Human genetics - 1 Jul 2007

Tan Yuan-De, Fornage Myriam, George Varghese, Xu Hongyan

Abstract excerpt

It is becoming clear that the etiology of complex diseases involves not only genetic and environmental factors but also gene-environment (GE) interactions. Therefore, it is important to take account of all these factors to improve the power of an epidemiological study design. We propose here a novel parent-child pair (PCP) design for this purpose. In comparison with conventional designs, this approach has the...

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PMID: 17492315
DOI: 10.1007/s00439-007-0369-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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