Article
Influence of KIR gene diversity on the course of HSV-1 infection: resistance to the disease is associated with the absence of KIR2DL2 and KIR2DS2.
Tissue antigens - 1 Jul 2007
Estefanía E, Gómez-Lozano N, Portero F, de Pablo R, Solís R, Sepúlveda S, Vaquero M, González M A, Suárez E, Roustán G, Vilches C
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) causes lifelong latent infections in most humans. Periodical virus reactivations from latency in the neurons of sensitive ganglia lead to transport to mucocutaneous regions and productive replication, which results in recurrent inflammatory herpetic lesions or in asymptomatic virus shedding. The medical consequences of such lesions and the frequency of recurrences vary greatly...
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