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Article

The role of killer immunoglobulin-like receptors in HTLV-1 infection

2015-01-01

Abstract excerpt

Human T-lymphotropic virus type 1 (HTLV-1) causes the debilitating neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a minority of infected individuals, while the majority are lifelong asymptomatic carriers (ACs). The effectiveness of the CD8+ T-cell response to HTLV-1 is a major determinant of the HTLV-1 proviral load (PVL) and the associated HAM/TSP risk. Host genot...

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Literature Corpus work
d8e54f07-2ecd-514d-ab60-35657f3f98da
DOI
10.25560/25539
Open publication

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