Article
The impact of variation at the KIR gene cluster on human disease.
Current topics in microbiology and immunology - 1 Jan 2006
Carrington M, Martin M P
Abstract excerpt
Leukocyte behavior is controlled by a balance of inhibitory and stimulatory signals generated on ligand binding to a complex set of receptors located on the cell surface. The killer cell immunoglobulin-like receptor (KIR) genes encode one such, family of receptors expressed by natural killer (NK) cells, key components of the innate immune system that participate in early responses against infected or transformed...
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