Article
Evaluation of the implication of KIR2DL2 receptor in multiple sclerosis and herpesvirus susceptibility.
Journal of neuroimmunology - 15 Jun 2014
Ben Fredj Nadia, Rizzo Roberta, Bortolotti Daria, Nefzi Faten, Chebel Saber, Rotola Antonella, Frih-Ayed Mahbouba, Di Luca Dario, Aouni Mahjoub
Abstract excerpt
To evaluate the possible effect of cell immunoglobulin-like receptors (KIRs) on viral infection in multiple sclerosis (MS) patients, we performed genotyping of KIR2DL2 and his HLA-C1 ligand and we analyzed the presence of all eight human herpesviruses (HHVs) in 60 MS patients and 112 healthy controls. Significantly higher frequencies were found for KIR2DL2 enhanced in the presence of its ligand HLA-C1 in MS...
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