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Article

Characterization of natural killer cell phenotype and function during recurrent human HSV-2 infection.

PloS one - 1 Jan 2011

Björkström Niklas K, Svensson Alexandra, Malmberg Karl-Johan, Eriksson Kristina, Ljunggren Hans-Gustaf

Abstract excerpt

Human natural killer (NK) cell differentiation, characterized by a loss of NKG2A in parallel with the acquisition of NKG2C, KIRs, and CD57 is stimulated by a number of virus infections, including infection with human cytomegalovirus (CMV), hantavirus, chikungunya virus, and HIV-1. Here, we addressed if HSV-2 infection in a similar way drives NK cell differentiation towards an NKG2A(-)NKG2C(+)KIR(+)CD57(+)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22110712
DOI: 10.1371/journal.pone.0027664
PMCID: PMC3216993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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