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Article

Host genetic factors in susceptibility to herpes simplex type 1 virus infection: contribution of polymorphic genes at the interface of innate and adaptive immunity.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2012

Moraru Manuela, Cisneros Elisa, Gómez-Lozano Natalia, de Pablo Rosario, Portero Francisca, Cañizares María, Vaquero Mercedes, Roustán Gastón, Millán Isabel, López-Botet Miguel, Vilches Carlos

Abstract excerpt

HSV-1 establishes life-long latency that can result in clinical relapses or in asymptomatic virus shedding. Although virtually all adults have been exposed to HSV-1, the clinical course varies remarkably. Genetic host variability could be related to this clinical diversity. In this study, we analyzed the contribution of gene families in chromosomes 1, 6, 12, and 19, which encode key regulators of the innate and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22490439
DOI: 10.4049/jimmunol.1103434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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