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Article

Host genetic factors in susceptibility to herpes simplex type 1 virus infection: contribution of polymorphic genes at the interface of innate and adaptive immunity.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2012

Moraru Manuela, Cisneros Elisa, Gómez-Lozano Natalia, de Pablo Rosario, Portero Francisca, Cañizares María, Vaquero Mercedes, Roustán Gastón, Millán Isabel, López-Botet Miguel, Vilches Carlos

Abstract excerpt

HSV-1 establishes life-long latency that can result in clinical relapses or in asymptomatic virus shedding. Although virtually all adults have been exposed to HSV-1, the clinical course varies remarkably. Genetic host variability could be related to this clinical diversity. In this study, we anal...

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Source

Identifiers

PMID: 22490439
DOI: 10.4049/jimmunol.1103434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22490439-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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