Article
Screening for SNPs and haplotypes in the CYP3A7 gene in Chinese populations.
Pharmacogenomics - 1 Jun 2007
Du Jing, Shi Yongyong, Zhang Aiping, Wang Lei, Xuan Jiekun, He Guang, Xu Lingyun, Xu Mingsheng, Shu Anli, Yu Lan, Li Xingwang, Meng Junwei, Feng Guoyin, Xing Qinghe, He Lin
Abstract excerpt
OBJECTIVE: To determine the frequencies and haplotypes of the cytochrome P450 (CYP)3A7 gene in three Chinese ethnic groups, namely, Han, She and Dong. METHODS: SNP analyses of the CYP3A7 gene were carried out on three groups of healthy Chinese subjects consisting of 539 Han, 264 She and 273 Dong subjects, using direct sequencing. Linkage disequilibrium, haplotype inference and Hardy-Weinberg equilibrium were also...
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