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Screening CYP3A single nucleotide polymorphisms in a Han Chinese population with a genotyping chip.

Pharmacogenomics - 1 Oct 2005

Liu Chin-Hung, Peck Konan, Huang Jin-Ding, Lin Min-Shung, Wang Chin-Hsiung, Hsu Wen-Pin, Wang Hong-Wen, Lee Hui-Ling, Lai Ming-Liang

Abstract excerpt

Human cytochrome P450 (CYP)3A is a major P450 enzyme found in the liver and gastrointestinal tract. It plays an important role in the metabolism of a wide variety of drugs, some endogenous steroids and harmful environmental contaminants. It has been shown that CYP3A alleles encoding enzymes with little or no activity are largely created by single nucleotide polymorphisms (SNPs) in the sequences of these genes....

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Identifiers

PMID: 16207150
DOI: 10.2217/14622416.6.7.731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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