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Article

Sequence diversity and haplotype structure at the human CYP3A cluster.

The pharmacogenomics journal - 1 Jan 2000

Thompson E E, Kuttab-Boulos H, Yang L, Roe B A, Di Rienzo A

Abstract excerpt

The four members of the human CYP3A subfamily play important roles in the clearance of xenobiotics, hormones, and environmental compounds. Many SNPs at the CYP3A locus have been characterized, with several showing large allele frequency differences across populations. In addition to the effects of CYP3A SNPs on drug metabolism, recent studies have highlighted the potential for CYP3A variation in susceptibility to...

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PMID: 16314882
DOI: 10.1038/sj.tpj.6500347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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