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Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic populations.

Archives of pharmacal research - 1 Jan 2015

Kim Jeong-Hyun, Cheong Hyun Sub, Park Byung Lae, Kim Lyoung Hyo, Shin Hee Jung, Na Han Sung, Chung Myeon Woo, Shin Hyoung Doo

Abstract excerpt

Recently, CYP2A6, CYP2B6, CYP2C8, and CYP2E1 have been reported to play a role in the metabolic effect of pharmacological and carcinogenic compounds. Moreover, genetic variations of drug metabolism genes have been implicated in the interindividual variation in drug disposition and pharmacological response. To define the distribution of single nucleotide polymorphisms (SNPs) in these four CYP2 family genes and to...

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PMID: 24988984
DOI: 10.1007/s12272-014-0348-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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