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Article

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment.

Pharmacogenetics and genomics - 1 Jul 2007

Ohlendorff Stine D, Tofteng Charlotte L, Jensen Jens-Erik B, Petersen Solveig, Civitelli Roberto, Fenger Mogens, Abrahamsen Bo, Hermann Anne P, Eiken Pia, Jørgensen Niklas R, Jrgensen Niklas R

Abstract excerpt

OBJECTIVES: The purinergic P2RX7 receptor (P2RX7) has been shown to play a role in the regulation of osteoblast and osteoclast activity. The aim of this study was to determine the presence of polymorphisms in exon 13 of the P2X7 gene and the association with osteoclast apoptosis in vitro and bone status in vivo. METHODS: A total of 1764 postmenopausal women were genotyped for three single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Purinergic P2

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Identifiers

PMID: 17558311
DOI: 10.1097/FPC.0b013e3280951625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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