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Article

Genetic interaction of purinergic P2X7 receptor and ER-α polymorphisms in susceptibility to osteoporosis in Chinese postmenopausal women.

Journal of bone and mineral metabolism - 1 Jul 2018

Wang Hui, Gong Chengxin, Liu Xingzi, Rao Shenqiang, Li Tao, He Luling, Nie Yijun, Wang Shuo, Zhong Peipei, Xue Yansong, Wang Jihong, Zhao Jiani, Zhou Yuru, Ding Lu, Tu Yunming, Yang Yuping, Xiong Chaopeng, Liang Shangdong, Xu Hong

Abstract excerpt

Osteoporosis (OP) is an increasing public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The aim of this study was to investigate the association of the purinergic P2X7 receptor (P2X7R) and estrogen receptor-α (ER-α) genes with OP risk, and the effect of the possible interaction between the two genes on predisposition to OP in Chinese postmenopausal...

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Identifiers

PMID: 28884379
DOI: 10.1007/s00774-017-0862-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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