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Article

Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to osteoporosis in Chinese postmenopausal women.

Purinergic signalling - 1 Sept 2017

Xu Hong, Gong Chengxin, He Luling, Rao Shenqiang, Liu Xingzi, Nie Yijun, Liu Changle, Li Tao, Ding Lu, Tu Yunming, Yang Yuping, Hu Fangfang, Fan Yongfang, Wang Hui, Wang Shuo, Xiong Chaopeng, Zhong Peipei, Tang Lan, Liang Shangdong

Abstract excerpt

Osteoporosis (OP) is a major public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The purinergic P2X7 receptor (P2X7R) has been shown to play a role in the regulation of osteoblast and osteoclast activity and has been considered as an important candidate gene for OP. A case-control study was performed to investigate the associations of functional...

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Identifiers

PMID: 28497417
DOI: 10.1007/s11302-017-9566-3
PMCID: PMC5563295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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