Article
Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Apr 2013
Wesselius A, Bours M J L, Henriksen Z, Syberg S, Petersen S, Schwarz P, Jørgensen N R, van Helden S, Dagnelie P C
Abstract excerpt
UNLABELLED: The P2X7 receptor is thought to be involved in bone physiology in a pro-osteogenic manner. Therefore, we examined associations between genetic variations in the P2X7 receptor gene and bone mineral density (BMD). We found an association between four non-synonymous polymorphism of the human P2X7 receptor and the risk of osteoporosis. INTRODUCTION: The purpose of this study was to determine whether...
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