Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury.

Purinergic signalling - 1 Mar 2016

Varley Ian, Greeves Julie P, Sale Craig, Friedman Eitan, Moran Daniel S, Yanovich Ran, Wilson Peter J, Gartland Alison, Hughes David C, Stellingwerff Trent, Ranson Craig, Fraser William D, Gallagher James A

Abstract excerpt

Military recruits and elite athletes are susceptible to stress fracture injuries. Genetic predisposition has been postulated to have a role in their development. The P2X7 receptor (P2X7R) gene, a key regulator of bone remodelling, is a genetic candidate that may contribute to stress fracture predisposition. The aim of this study is to evaluate the putative contribution of P2X7R to stress fracture injury in two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Athletes
Share to Bone Remodeling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Israel

Share to Military Personnel

Share to Receptors, Purinergic P2X7

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26825304
DOI: 10.1007/s11302-016-9495-6
PMCID: PMC4749527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury.PMID 26825304Read ↗

Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis.Semantic proximity Read ↗

The association of novel polymorphisms with stress fracture injury in Elite Athletes: Further insights from the SFEA cohort.Semantic proximity Read ↗

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures.Semantic proximity Read ↗

Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.Semantic proximity Read ↗

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment.Semantic proximity Read ↗

RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes.Semantic proximity Read ↗

Significance of P2X7 receptor variants to human health and disease.Semantic proximity Read ↗

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women.Semantic proximity Read ↗

P2X7 receptors: role in bone cell formation and function.Semantic proximity Read ↗

Genetic predisposition for femoral neck stress fractures in military conscripts.Semantic proximity Read ↗

Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.Semantic proximity Read ↗

Genetic variation in P2RX7 and pain tolerance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.