Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beta-synuclein gene variants and Parkinson's disease: a preliminary case-control study.

Neuroscience letters - 15 Jun 2007

Brighina Laura, Okubadejo Njide U, Schneider Nicole K, Lesnick Timothy G, de Andrade Mariza, Cunningham Julie M, Farrer Matthew J, Lincoln Sarah J, Rocca Walter A, Maraganore Demetrius M

Abstract excerpt

Aggregation and fibrillization of the alpha-synuclein protein, which is the main component of Lewy bodies, may represent important processes in the pathogenesis of Parkinson's disease (PD). Several in vivo and in vitro studies suggest that beta-synuclein may be a natural negative regulator of alpha-synuclein aggregation and fibrillization. The goal of the present study was to investigate the association of two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Parkinson Disease

Share to Sex Characteristics

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 17556099
DOI: 10.1016/j.neulet.2007.05.021
PMCID: PMC1978171

Genes

SNCB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beta-synuclein gene variants and Parkinson's disease: a preliminary case-control study.PMID 17556099Read ↗

INDEL Length and Haplotypes in the β-Synuclein Gene: A Key to Differentiate Dementia with Lewy Bodies?Semantic proximity Read ↗

Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease.Semantic proximity Read ↗

Case-control study of the alpha-synuclein interacting protein gene and Parkinson's disease.Semantic proximity Read ↗

Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease.Semantic proximity Read ↗

Identification of a risk haplotype of the alpha-synuclein gene in Japanese with sporadic Parkinson's disease.Semantic proximity Read ↗

Multiple regions of alpha-synuclein are associated with Parkinson's disease.Semantic proximity Read ↗

Evaluation of the role of SNCA variants in survival without neurological disease.Semantic proximity Read ↗

Beta-synuclein gene alterations in dementia with Lewy bodies.Semantic proximity Read ↗

No pathogenic mutations in the beta-synuclein gene in Parkinson's disease.Semantic proximity Read ↗

SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.Semantic proximity Read ↗

Genetic association between Alzheimer disease and the alpha-synuclein gene.Semantic proximity Read ↗

Lack of Epistatic Interaction of<i>SNCA</i>with<i>APOE</i>in SynucleinopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.