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Genetic association between Alzheimer disease and the alpha-synuclein gene.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Matsubara M, Yamagata H, Kamino K, Nomura T, Kohara K, Kondo I, Miki T

Abstract excerpt

alpha-Synuclein has been isolated as a component of amyloid in addition to the major A beta peptide in Alzheimer disease (AD). However, there are conflicting reports regarding the association of alpha-synuclein gene polymorphism with AD. Using a novel and common polymorphism in intron 3, we examined the relationship between AD and alpha-synuclein and apolipoprotein E (ApoE) genes in 183 Japanese AD patients and...

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PMID: 11173882
DOI: 10.1159/000051243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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