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Article

Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.

The Journal of allergy and clinical immunology - 1 Jun 2007

Thompson Emma E, Pan Lin, Ostrovnaya Irina, Weiss Lauren A, Gern James E, Lemanske Robert F, Nicolae Dan L, Ober Carole

Abstract excerpt

BACKGROUND: The integrin beta3 gene (ITGB3) encodes a subunit of the platelet and monocyte-specific fibrinogen receptor and the widely expressed vitronectin receptor, which have diverse roles in cell migration, adhesion, and signaling. Previous work from our laboratory reported associations between single nucleotide polymorphisms (SNPs) in ITGB3 and asthma and allergic sensitization in 4 populations. OBJECTIVE:...

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Source

Identifiers

PMID: 17556058
DOI: 10.1016/j.jaci.2007.03.029

Genes

ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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