Article
Genetic variation of ITGB3 is associated with asthma in Chinese Han children.
PloS one - 1 Jan 2013
Zhang Yan, Han Yuling, Dong Liang, Yu Huafeng, Cheng Lu, Zhao Xiuxia, Ding Mingjie
Abstract excerpt
Previous studies have demonstrated that integrins are involved in the aetiology of asthma. Several single-nucleotide polymorphisms (SNPs) in the integrin β3 (ITGB3) gene are significantly associated with asthma in Western populations. Given the important roles of environmental exposures in the development of asthma, we evaluated the associations between six SNPs in ITGB3 and asthma in Chinese Han children. A...
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