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Article

Mold allergen sensitization in adult asthma according to integrin β3 polymorphisms and Toll-like receptor 2/+596 genotype.

The Journal of allergy and clinical immunology - 1 Jul 2011

Smit Lidwien A M, Bouzigon Emmanuelle, Bousquet Jean, Le Moual Nicole, Nadif Rachel, Pin Isabelle, Lathrop Mark, Demenais Florence, Kauffmann Francine, Siroux Valérie

Abstract excerpt

BACKGROUND: Integrin β3 (ITGB3) and Toll-like receptor 2 (TLR2) are candidate genes for asthma and sensitization to mold allergens. Integrin β3 forms a complex with TLR2, and this biological interaction is required for the response of monocytes to TLR2 agonists such as fungal glucan. OBJECTIVE: To study whether genetic interaction between single nucleotide polymorphisms (SNPs) in genes encoding the TLR2-ITGB3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21570717
DOI: 10.1016/j.jaci.2011.04.007

Genes

TLR2
ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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