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Article

CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies.

The Journal of allergy and clinical immunology - 1 Dec 2015

McGeachie Michael J, Wu Ann C, Tse Sze Man, Clemmer George L, Sordillo Joanne, Himes Blanca E, Lasky-Su Jessica, Chase Robert P, Martinez Fernando D, Weeke Peter, Shaffer Christian M, Xu Hua, Denny Josh C, Roden Dan M, Panettieri Reynold A, Raby Benjamin A, Weiss Scott T, Tantisira Kelan G

Abstract excerpt

BACKGROUND: Asthma exacerbations are a major cause of morbidity and medical cost. OBJECTIVE: The objective of this study was to identify genetic predictors of exacerbations in asthmatic subjects. METHODS: We performed a genome-wide association study meta-analysis of acute asthma exacerbation in 2 pediatric clinical trials: the Childhood Asthma Management Program (n = 581) and the Childhood Asthma Research and...

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Source

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Identifiers

PMID: 26073756
DOI: 10.1016/j.jaci.2015.04.039
PMCID: PMC4676949

Genes

CTNNA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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