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Article

Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma.

Human genetics - 1 Sept 2004

Hasegawa Koichi, Tamari Mayumi, Shao Chenchen, Shimizu Makiko, Takahashi Naomi, Mao Xiao-Quan, Yamasaki Akiko, Kamada Fumiaki, Doi Satoru, Fujiwara Hiroshi, Miyatake Akihiko, Fujita Kimie, Tamura Gen, Matsubara Yoichi, Shirakawa Taro, Suzuki Yoichi

Abstract excerpt

Bronchial asthma (BA) is a common chronic inflammatory disease characterized by hyperresponsive airways, excess mucus production, eosinophil activation, and the production of IgE. The complement system plays an immunoregulatory role at the interface of innate and acquired immunities. Recent studies have provided evidence that C3, C3a receptor, and C5 are linked to airway hyperresponsiveness. To determine whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15278436
DOI: 10.1007/s00439-004-1157-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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