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Article

Requirement for ErbB2/ErbB signaling in developing cartilage and bone

7 Jun 2007

Abstract excerpt

During endochondral ossification, the skeletal elements of vertebrate limbs form and elongate via coordinated control of chondrocyte and osteoblast differentiation and proliferation. The role of signaling by the ErbB family of receptor tyrosine kinases, which consists of ErbB1 (epidermal growth factor receptor or EGFR), ErbB2, ErbB3 and ErbB4, has been little studied during cartilage and bone development....

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PMID: 17555517
DOI: 10.1111/j.1440-169x.2007.00941.x

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