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Article

Hand2 regulates chondrogenesis in vitro and in vivo.

Bone - 1 May 2010

Abe Makoto, Michikami Ikumi, Fukushi Toshiya, Abe Akiko, Maeda Yoshinobu, Ooshima Takashi, Wakisaka Satoshi

Abstract excerpt

Hand2 is a transcription factor of the basic helix-loop-helix family that plays essential roles during development. Hand2 determines the anterior-posterior axis during limb development and there is also substantial evidence that Hand2 regulates limb skeletogenesis. However, little is known about how Hand2 might regulate skeletogenesis. Here we show that, in a limb bud micromass culture system, over-expression of...

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Source

Identifiers

PMID: 19932774
DOI: 10.1016/j.bone.2009.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hand2 regulates chondrogenesis in vitro and in vivo.PMID 19932774Read ↗

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