Article
Genome-wide SNP analysis reveals no gain in power for association studies of common variants in the Finnish Saami.
European journal of human genetics : EJHG - 1 May 2010
Huyghe Jeroen R, Fransen Erik, Hannula Samuli, Van Laer Lut, Van Eyken Els, Mäki-Torkko Elina, Lysholm-Bernacchi Alana, Aikio Pekka, Stephan Dietrich A, Sorri Martti, Huentelman Matthew J, Van Camp Guy
Abstract excerpt
The Saami from Fennoscandia are believed to represent an ancient, genetically isolated population with no evidence of population expansion. Theoretical work has indicated that under this demographic scenario, extensive linkage disequilibrium (LD) is generated by genetic drift. Therefore, it has b...
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