Article
A genome-wide analysis of population structure in the Finnish Saami with implications for genetic association studies.
European journal of human genetics : EJHG - 1 Mar 2011
Huyghe Jeroen R, Fransen Erik, Hannula Samuli, Van Laer Lut, Van Eyken Els, Mäki-Torkko Elina, Aikio Pekka, Sorri Martti, Huentelman Matthew J, Van Camp Guy
Abstract excerpt
The understanding of patterns of genetic variation within and among human populations is a prerequisite for successful genetic association mapping studies of complex diseases and traits. Some populations are more favorable for association mapping studies than others. The Saami from northern Scandinavia and the Kola Peninsula represent a population isolate that, among European populations, has been less...
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