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Article

High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism.

Blood - 1 Oct 2007

Kawase Takakazu, Morishima Yasuo, Matsuo Keitaro, Kashiwase Koichi, Inoko Hidetoshi, Saji Hiroh, Kato Shunichi, Juji Takeo, Kodera Yoshihisa, Sasazuki Takehiko

Abstract excerpt

In allogenic hematopoietic stem-cell transplantation, an effect of HLA locus mismatch in allele level on clinical outcome has been clarified. However, the effect of each HLA allele mismatch combination is little known, and its molecular mechanism to induce acute graft-versus-host disease (aGVHD) remains to be elucidated. A total of 5210 donor-patient pairs who underwent transplantation through Japan Marrow Donor...

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Identifiers

PMID: 17554059
DOI: 10.1182/blood-2007-02-072405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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