Article
Impact of HLA Allele Mismatch at HLA-A, -B, -C, and -DRB1 in Single Cord Blood Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Mar 2020
Yokoyama Hisayuki, Morishima Yasuo, Fuji Shigeo, Uchida Naoyuki, Takahashi Satoshi, Onizuka Makoto, Tanaka Masatsugu, Yuju Ohno, Eto Tetsuya, Ozawa Yukiyasu, Takada Satoru, Takanashi Minoko, Kato Koji, Kanda Yoshinobu, Ichinohe Tatsuo, Atsuta Yoshiko, Kanda Junya
Abstract excerpt
The impact of allele-level HLA mismatch on outcomes of cord blood transplantation has not been well established. We retrospectively analyzed the effects of HLA allele matching at HLA-A, -B, -C, and -DRB1 in cord blood transplantation for acute myeloid leukemia, acute lymphoblastic leukemia, and myelodysplastic syndrome. In multivariate analysis, overall survival (OS) significantly deteriorated in the 4-allele or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.