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Article

Role of HLA in hematopoietic SCT.

Bone marrow transplantation - 1 Oct 2008

Nowak J

Abstract excerpt

HLA disparity between hematopoietic stem cell (HSC) donor and recipient triggers T-cell and NK-cell allorecognition, and induces the GVHD, GVL effect and/or may cause an engraftment failure. This review will cover the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. We describe the main subsets of related and unrelated HSC donors and outline the main...

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Topics

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Share to Donor Selection
Share to Graft Rejection
Share to Graft vs Host Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Killer Cells, Natural

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Share to Transplantation, Homologous

Source

Identifiers

PMID: 18978750
DOI: 10.1038/bmt.2008.288

Genes

SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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