Article
Biological significance of HLA locus matching in unrelated donor bone marrow transplantation.
Blood - 12 Feb 2015
Morishima Yasuo, Kashiwase Koichi, Matsuo Keitaro, Azuma Fumihiro, Morishima Satoko, Onizuka Makoto, Yabe Toshio, Murata Makoto, Doki Noriko, Eto Tetsuya, Mori Takehiko, Miyamura Koichi, Sao Hiroshi, Ichinohe Tatsuo, Saji Hiroo, Kato Shunichi, Atsuta Yoshiko, Kawa Keisei, Kodera Yoshihisa, Sasazuki Takehiko
Abstract excerpt
We hypothesized that the compatibility of each HLA loci between donor and patient induced divergent transplant-related immunologic responses, which attributed to the individualized manifestation of clinical outcomes. Here, we analyzed 7898 Japanese pairs transplanted with T-cell-replete marrow from an unrelated donor with complete HLA allele typing data. Multivariable competing risk regression analyses were...
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