Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline.

Developmental cell - 1 Jun 2007

Pane Attilio, Wehr Kristina, Schüpbach Trudi

Abstract excerpt

RNAi is a widespread mechanism by which organisms regulate gene expression and defend their genomes against viruses and transposable elements. Here we report the identification of Drosophila zucchini (zuc) and squash (squ), which function in germline RNAi processes. Zuc and Squ contain domains with homologies to nucleases. Mutant females are sterile and show dorsoventral patterning defects during oogenesis. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endonucleases
Share to Endoribonucleases
Share to Gene Products, gag

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ Cells

Share to Oogenesis

Share to Peptide Initiation Factors

Share to RNA, Fungal

Share to Transforming Growth Factor alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 17543859
DOI: 10.1016/j.devcel.2007.03.022
PMCID: PMC1945814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline.PMID 17543859Read ↗

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila.Semantic proximity Read ↗

The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on MitochondriaSemantic proximity Read ↗

The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila.Semantic proximity Read ↗

Mutations in the Insulator Protein Suppressor of Hairy Wing Induce Genome InstabilitySemantic proximity Read ↗

Stonewall prevents expression of testis-enriched genes and binds to insulator elements in <i>D. melanogaster</i>Semantic proximity Read ↗

Systematic Identification of Germ Granule Proteins Reveals Specialized Roles in RNAi and Small RNA InheritanceSemantic proximity Read ↗

Ovo is a master regulator of the piRNA pathway in animal ovarian germ cellsSemantic proximity Read ↗

Mutations in the insulator protein Suppressor of Hairy wing induce genome instability.Semantic proximity Read ↗

A cytoplasmic Argonaute protein promotes the inheritance of RNAiSemantic proximity Read ↗

Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains.Semantic proximity Read ↗

Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline.Semantic proximity Read ↗

The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.