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Article

The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila.

The EMBO journal - 15 Feb 2012

Anand Amit, Kai Toshie

Abstract excerpt

In Drosophila ovaries, distinct Piwi-interacting RNA (piRNA) pathways defend against transposons in somatic and germline cells. Germline piRNAs predominantly arise from bidirectional clusters and are amplified by the ping-pong cycle. In this study, we characterize a novel Drosophila gene, kumo and show that it encodes a conserved germline piRNA pathway component. Kumo contains five tudor domains and localizes to...

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Identifiers

PMID: 22157814
DOI: 10.1038/emboj.2011.449
PMCID: PMC3280549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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