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Article

IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2007

Wang Yongmei, Nishida Shigeki, Boudignon Benjamin M, Burghardt Andrew, Elalieh Hashem Z, Hamilton Michelle M, Majumdar Sharmila, Halloran Bernard P, Clemens Thomas L, Bikle Daniel D

Abstract excerpt

UNLABELLED: We showed that the IGF-IR-null mutation in mature osteoblasts leads to less bone and decreased periosteal bone formation and impaired the stimulatory effects of PTH on osteoprogenitor cell proliferation and differentiation. INTRODUCTION: This study was carried out to examine the role...

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Source

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Identifiers

PMID: 17539737
DOI: 10.1359/jbmr.070517
PMCID: PMC10702248

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17539737-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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