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Article

The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: physiology and pharmacology.

Molecular and cellular endocrinology - 25 Jun 2008

Garrett R W, Emerson S G

Abstract excerpt

Hematopoietic stem cells (HSC) capable of both self-renewal and differentiation into all blood lineages reside within the bone marrow in specialized microenvironmental niches. While the precise location and composition of these niches largely remains unknown, it is now believed that osteoblasts at the endosteal surface play critical roles. Among the molecules demonstrated to influence the function of these niches...

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Source

Identifiers

PMID: 18400373
DOI: 10.1016/j.mce.2008.02.022

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: physiology and pharmacology.PMID 18400373Read ↗

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40 YEARS OF IGF1: Insulin-like growth factors: actions on the skeletonSemantic proximity Read ↗

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The Osteoblastic Niche in Hematopoiesis and Hematological Myeloid MalignanciesSemantic proximity Read ↗

IGF1R signaling in perinatal mesenchymal stem cells determines definitive hematopoiesis in bone marrowSemantic proximity Read ↗

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