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Article

The bradykinin type 2 receptor BE1 polymorphism and ethnicity influence systolic blood pressure and vascular resistance.

Clinical pharmacology and therapeutics - 1 Jan 2008

Pretorius M M, Gainer J V, Van Guilder G P, Coelho E B, Luther J M, Fong P, Rosenbaum D D, Malave H A, Yu C, Ritchie M D, Vaughan D E, Brown N J

Abstract excerpt

We examined the effect of -58 C/T and BE1 +9/-9 polymorphisms in the bradykinin B2 receptor gene on forearm vascular resistance (FVR) before and during intrabrachial artery infusion of the B2 receptor-, endothelium-dependent agonist bradykinin and the endothelium-independent agonist sodium nitroprusside in 228 normotensive subjects. In 166 white Americans, systolic blood pressure (SBP) and pulse pressure were...

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Identifiers

PMID: 17522594
DOI: 10.1038/sj.clpt.6100250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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