Article
Sequence variation of bradykinin receptors B1 and B2 and association with hypertension.
Journal of hypertension - 1 Jan 2005
Cui Jing, Melista Efthymia, Chazaro Irmarie, Zhang Yuejian, Zhou Xiaofeng, Manolis Athanasios J, Baldwin Clinton T, Destefano Anita L, Gavras Haralambos
Abstract excerpt
OBJECTIVE: To identify variants in the complete genomic sequence of the two subtypes of bradykinin receptors: B1 (BDKRB1) and B2 (BDKRB2) and to examine the association of these variants with essential hypertension. DESIGN: A case-control design comparing hypertensive and normotensive individuals was used. METHOD: A 64.4 kb genomic region containing the BDKRB1 and BDKRB2 genes was sequenced in 30 African-American...
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