Article
Polymorphism of the bradykinin type 2 receptor gene modulates blood pressure profile and microvascular function in prepubescent children.
Peptides - 1 Mar 2021
Souza Livia Victorino, de Almeida Sandro Soares, De Meneck Franciele, Thomazini Fernanda, Araujo Ronaldo Carvalho, Franco do Maria Carmo
Abstract excerpt
Previous reports reveal that +9/-9 polymorphism of the bradykinin B2 receptor (BDKRB2) is suggestive of cardiometabolic diseases. The aim of this study was to examine the impact of BDKRB2 + 9/-9 polymorphism genotypes on the blood pressure parameters and microvascular function in prepubescent children. We screened for BDKRB2 + 9/-9 polymorphism in the DNA of 145 children (86 boys and 59 girls), and its...
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