Article
Vascular reactivity and ACE activity response to exercise training are modulated by the +9/-9 bradykinin B₂ receptor gene functional polymorphism.
Physiological genomics - 17 Jun 2013
Alves Cléber Rene, Alves Guilherme Barreto, Pereira Alexandre Costa, Trombetta Ivani Credidio, Dias Rodrigo Gonçalves, Mota Glória F A, Fernandes Tiago, Krieger José Eduardo, Negrão Carlos Eduardo, Oliveira Edilamar Menezes
Abstract excerpt
The bradykinin receptor B₂ (BDKRB₂) gene +9/-9 polymorphism has been associated with higher gene transcriptional activity, and characteristics of cardiovascular phenotypes and physical performance. We hypothesized that vasodilation and ACE activity response to exercise training is modulated by BDKRB₂ gene. We genotyped 71 healthy volunteers were genotyped for the BDKRB₂ gene polymorphism. Heart rate (HR), mean...
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