Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.

Pharmacogenetics and genomics - 1 Sept 2008

Kurnik Daniel, Friedman Eitan A, Muszkat Mordechai, Sofowora Gbenga G, Xie Hong-Guang, Dupont William D, Wood Alastair J J, Stein C Michael

Abstract excerpt

OBJECTIVES: Cardiovascular responses to stressors are regulated by sympathetic activity, increased in black Americans, and associated with future cardiovascular morbidity. Our aim was to determine whether two functional variants in genes regulating sympathetic activity, a deletion in the alpha2C-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular System
Share to Catecholamines
Share to Cold Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Rate

Share to Heterotrimeric GTP-Binding Proteins

Share to Protein Subunits

Share to Receptors, Adrenergic, alpha-2

Share to Stress, Psychological

Source

Open in PubMed Open full text

Identifiers

PMID: 18698227
DOI: 10.1097/FPC.0b013e3282fee5a1
PMCID: PMC2689621

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18698227-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.PMID 18698227Read ↗

Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine.Semantic proximity Read ↗

Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects.Semantic proximity Read ↗

Alpha-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.Semantic proximity Read ↗

Genetic variation in the alpha1B-adrenergic receptor and vascular response.Semantic proximity Read ↗

Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals.Semantic proximity Read ↗

Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.Semantic proximity Read ↗

Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension.Semantic proximity Read ↗

Effects of polymorphisms in beta1-adrenoceptor and alpha-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study.Semantic proximity Read ↗

Pharmacology and Physiology of Human Adrenergic Receptor polymorphismsSemantic proximity Read ↗

Beta-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.Semantic proximity Read ↗

Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death.Semantic proximity Read ↗

beta(2)-Adrenergic receptor polymorphisms and determinants of cardiovascular risk: the Cardiovascular Health Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.