Article
Bradykinin B2 receptor gene (-58T/C) polymorphism influences baroreflex sensitivity in never-treated hypertensive patients.
Journal of hypertension - 1 Jan 2005
Milan Alberto, Mulatero Paolo, Williams Tracy A, Carra Renata, Schiavone Domenica, Martuzzi Roberto, Rabbia Franco, Veglio Franco
Abstract excerpt
BACKGROUND: Most evidence currently favours a fundamental role of the autonomic nervous system in the pathogenesis of essential hypertension. Recent studies suggest that about 40% of baroreflex variation, an index of cardiac autonomic control, is influenced by genetic factors. METHODS AND RESULTS: The aim of this study was to investigate the effect of a common polymorphic variant of the bradykinin B2 receptor...
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