Article
Lifespan extension by suppression of autophagy genes in Caenorhabditis elegans.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2009
Hashimoto Yasufumi, Ookuma Sadatsugu, Nishida Eisuke
Abstract excerpt
Lifespan is regulated by a complex combination of environmental and genetic factors. Autophagy, which is a bulk degradation system of macromolecules and organelles, has an important role in various biological events. In Caenorhabditis elegans, several autophagy genes have been shown to have a rol...
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