Article
Multiplex assay for comprehensive genotyping of genes involved in drug metabolism, excretion, and transport.
Clinical chemistry - 1 Jul 2007
Daly Thomas M, Dumaual Carmen M, Miao Xin, Farmen Mark W, Njau Reuben K, Fu Dong-Jing, Bauer Nancy L, Close Sandra, Watanabe Nancy, Bruckner Carsten, Hardenbol Paul, Hockett Richard D
Abstract excerpt
BACKGROUND: Drug metabolism is a multistep process by which the body disposes of xenobiotic agents such as therapeutic drugs. Genetic variation in the enzymes involved in this process can lead to variability in a patient's response to medication. METHODS: We used molecular-inversion probe technol...
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