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Article

Development of a broad-based ADME panel for use in pharmacogenomic studies.

Pharmacogenomics - 1 Jun 2014

Brown Andrew M K, Renaud Yannick, Ross Colin, Hansen Mark, Mongrain Ian, Valois Diane, Carleton Bruce C, Hayden Michael R, Dubé Marie-Pierre, Tardif Jean-Claude, Phillips Michael S

Abstract excerpt

AIM: To optimally address the interindividual variability observed in pharmacokinetic drug response, we have created a custom genotyping panel that interrogates most of the key genetic variations present in a set of 181 prioritized genes responsible for the absorption, distribution, metabolism and excretion (ADME) of many therapeutic agents. This consensus list of genes and variants was based on the ADME core and...

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Identifiers

PMID: 25141894
DOI: 10.2217/pgs.14.81

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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