Article
TaqMan® drug metabolism genotyping assays for the detection of human polymorphisms involved in drug metabolism.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Hartshorne Toinette
Abstract excerpt
Polymorphisms associated with genes that code for various drug-metabolizing enzymes (DMEs) and associated transport proteins can influence the rate of drug metabolism within individuals, thus potentially affecting drug efficacy and the occurrence of side effects. There are 2,700 unique TaqMan(®) Drug Metabolism Genotyping Assays (Life Technologies) for detecting single nucleotide polymorphisms (SNPs), insertions...
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