Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiplex genotyping of cytochrome p450 single-nucleotide polymorphisms by use of MALDI-TOF mass spectrometry.

Clinical chemistry - 1 May 2007

Misra Ashish, Hong Jun-Yan, Kim Sobin

Abstract excerpt

BACKGROUND: Polymorphisms in cytochrome P450 (CYP450) genes contribute to interindividual differences in the metabolism of xenobiotic chemicals, including the vast majority of drugs, and may lead to toxicity and adverse drug reactions. Studies on these polymorphisms in research and diagnostic settings typically involve large-scale genotyping and hence require high-throughput assays. METHODS: We used the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Cell Line
Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Capillary

Share to Heterozygote

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 17384008
DOI: 10.1373/clinchem.2006.080739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiplex genotyping of cytochrome p450 single-nucleotide polymorphisms by use of MALDI-TOF mass spectrometry.PMID 17384008Read ↗

Multiplex genotyping of CYP3A4, CYP3A5, CYP2C9 and CYP2C19 SNPs using MALDI-TOF mass spectrometry.Semantic proximity Read ↗

MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms.Semantic proximity Read ↗

Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.Semantic proximity Read ↗

A multiplex assay for detecting genetic variations in CYP2C9, VKORC1, and GGCX involved in warfarin metabolism.Semantic proximity Read ↗

Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation.Semantic proximity Read ↗

Genotyping technologies: application to biotransformation enzyme genetic polymorphism screening.Semantic proximity Read ↗

Development of a single-tube PCR-pyrosequencing method for the simultaneous and rapid detection of four variant alleles of CYP2C9 gene polymorphism.Semantic proximity Read ↗

Genotyping technologies: application to biotransformation enzyme genetic polymorphism screening.Semantic proximity Read ↗

Technologies for detecting genetic polymorphisms in pharmacogenomics.Semantic proximity Read ↗

Validation of a multi-gene qPCR-based pharmacogenomics panel across major ethnic groups in Singapore and Indonesia.Semantic proximity Read ↗

Technologies for individual genotyping: detection of genetic polymorphisms in drug targets and disease genes.Semantic proximity Read ↗

MALDI-TOF mass spectrometry-based SNP genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.