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Article

Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2008

Covault Jonathan, Gelernter Joel, Jensen Kevin, Anton Raymond, Kranzler Henry R

Abstract excerpt

Following an initial report, there have been multiple replications of an association of alcohol dependence (AD) to markers within a haplotype block that includes the 3'-half of the gene encoding the GABA(A) alpha-2 subunit (GABRA2), on chromosome 4p. We examined the intergenic extent of this haplotype block and the association to AD of markers in the adjacent 5' haplotype block in GABRG1, which encodes the...

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Share to Alcoholism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Receptors, GABA-A

Source

Open in PubMed Open full text

Identifiers

PMID: 17507911
DOI: 10.1038/sj.npp.1301456
PMCID: PMC2743531

Genes

GABRA2
GABRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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